Ricerca sul cancro della pelle
Ricerca sul melanoma e sul carcinoma cheratinocitario con la tecnologia EIS di Nevisense
Scopri la ricerca clinica su Nevisense nell’ambito della diagnosi del cancro della pelle. Questi studi esaminano in che modo la spettroscopia di impedenza elettrica (EIS) possa supportare la valutazione delle lesioni sospette, tra cui il melanoma e i tumori cheratinocitari.
Basato sulla ricerca accademica
Ricerca con la tecnologia EIS di Nevisense
Comparing Improvements in Biopsy Decision Making with Electrical Impedance Spectroscopy Between US and German Dermatologists, D Zakria, N Brownstone, M Shah, MD3, J Burshtein, L DeBusk, A Rosenberg, D Rigel, SKIN Jan 2025, Vol 9 Issue 1, DOI https://doi.org/10.25251/skin.9.1.5
Advances in Technology for Melanoma Diagnosis and Prognosis: En Expert Consensus Panel, J Burshtein, D Zakria, B Berman, S Desai, A Farberg, G Goldenberg, B Glick, M Nestor, K Nouri, T Rosen, M Lebwohl, D Rigel, JDD Sep 24, Vol 23 Issue 9, 774 DOI: 10.36849/JDD.8365R1
Utilizing Data from Electrical Impedance Spectroscopy Significantly Improves the Decision to Biopsy Pigmented Skin Lesions Beyond Clinical Evaluation and Dermoscopy, D Zakria, N Brownstone, K Fritz, C Salavastru, D Rigel SKIN May 2024, Volume 8, Issue 3, DOI https://doi.org/10.25251/skin.8.3.5
Management of Pigmented Lesions in Primary Care: Effects of Electrical Impedance Spectroscopy Use, Shayan Owji, Joseph Han, Margaret Glausser, Daniel Napolitano and Jonathan Ungar, The Annals of Family Medicine January 2023, 21 (Supplement 1) 4189; DOI: https://doi.org/10.1370/afm.21.s1.4189
2022 Zakria, Electrical impedance spectroscopy significantly enhances correct biopsy choice for pigmented skin lesions beyond clinical evaliation and dermoscopy, D Zakria, N Brownstone, J Han, S Owji, M Dirr, D Rigel, Melanoma Research Oct 2022, DOI: 10.1097/CMR.0000000000000859 https://jofskin.org/index.php/skin/article/view/1568
Diagnostic Efficiacy of Electrical Impedance Spectroscopy versus Dermoscopy for Pigmented Skin Lesions: A pilot study, S Owji, J Han, H He, I Lopera, M Tassavor, N Brownstone, N Gulati, B Ungar, J Ungar, SKIN May 2022, Vol 6, Issue 3
https://jofskin.org/index.php/skin/article/view/1568
Electrical Impedance Spectroscopy improves skin cancer detection and reduces the number of biopsies, C. Liebich, J. Bartsch, I. Schubert, M-L. v. Bruehl, C. Sander, Dermato, 2022, 2, 21-29. DOI.org/10.3390/dermato2020004
Impact of Electrical Impedance Spectroscopy on Clinician Confidence and Diagnostic Accuracy in Evaluating Melanocytic Skin Lesions Suspicious for Melanoma: A Pilot Study, A. Kolla, L. Fried, P. Shah, T. Liebman, J. Stein, D. Polsky, SKIN January 2022 Vol6, Issue doi.org/10.25251/skin.6.1.4
Impact of Electrical Impedance Spectroscopy on Dermatologists’ Number-Needed-to-Biopsy Metric and Biopsy Decisions for Pigmented Skin Lesions, G. Litchman, R Teplitz, J. Marson, D Rigel, JAAD October 2021, doi.org/10.1016/j.jaad.2020.09.011
Retrospective evaluation of the performance of the electrical impedance spectroscopy system Nevisense in detecting keratinocyte cancers, C. Liebich, M-L Bruehl, I Schubert, R Oberhoffer, C Sander, Skin Research and Technology, 2021;00:1-7; DOI:10.1111/srt.13007
Diagnostic Accuracy of Electrical Impedance Spectroscopy in Non-melanoma Skin Cancer, E Sarac, C Garbe et. al, DOI: 10.2340/00015555-3689, Acta Derm Venereol 2020; 100: adv00328
Electrical Impedance Spectroscopy: Augmented Intelligence Technology for the Early Detection of Melanoma, G Goldenberg, Practical Dermatology April 2020, p44-45.
Impact of Electrical Impedance Spectroscopy on Dermatologists’ Number-Needed-to-Biopsy Metric and Biopsy Decisions for Pigmented Skin Lesions. Litchman, D Rigel et al ,https://doi.org/10.1016/j.jaad.2020.09.011
Integrating Electrical Impedance Spectroscopy into Clinical Decisions for Pigmented Skin Lesions Improves Diagnostic Accuracy: A Multitiered Study, G Litchman, D Rigel et al, SKIN July 2020 Volume 4, Issue 4
Integrating Electrical Impedance Score into Decision to Biopsy Increases Biopsy Efficiency,
G Prado, D Rigel, ePoster 10062, AAD 2019, www.aad.org/eposters/Submissions/getFile.aspx?id=10062&type=sub
Electrical impedance spectroscopy of 79 melanocytic lesions in a National Health Service skin cancer clinic, Haddadeen C.; Maguire C.; Henderson C. 99th Annual Meeting of the British Association of Dermatologists, conference abstract, British Journal of Dermatology 181 Supplement 1 (62-63). 2019, http://dx.doi.org/10.1111/bjd.17893
Electrical Impedance Spectroscopy Improves Diagnostic Accuracy of Pigmented Lesions,
G Prado, D Rigel et al, ePoster 10229, AAD 2019, www.aad.org/eposters/Submissions/getFile.aspx?id=10229&type=sub
EIS: Atypien von Hautveränderungen präzise messen,
J Welzel, U Reinhold, Der Deutsche Dermatologe 2018 Nov, pages 847-851, DOI: 10.1007/s15011-018-2189-3
Assessment of Clinician Accuracy for Diagnosing Melanoma Based on Electrical Impedance Spectroscopy Score Plus Morphology Versus Lesion Morphology Alone, abstract,
R Svoboda, G Prado, R Mirsky, D Rigel, JAAD 2018. DOI: 10.1016/j.jaad.2018.08.048
Electrical Impedance Spectroscopy Versus Clinical Inspection Approaches: Melanoma Efficacy Detection Comparison, abstract,
R Svoboda, A Franco, D Rigel, SKIN 2018, DOI: 10.25251/skin.2.3.2
Noninvasive diagnosis in dermatology, abstract,
J Welzel, S Schuh, JDDG 2017 999-1016, DOI: 10.1111/ddg.13347
Electrical Impedance Spectroscopy in Skin Cancer Diagnosis Abstract
R Braun, J Mangana, S Goldinger, Lars French, R Dummer, A Marghoob, Dermatological Clinic 35 (2017) 489-493, http://dx.doi.org/10.1016/j.det.2017.06.009
Utilisation of an Electrical Impedance Spectroscopy System in an NHS setting in a pigmented lesion clinic as an adjuvant to dermoscopy and clinical history
Catriona Henderson, Birgit Pees, Poster the 97th Annual Meeting of the British Association of Dermatologists in Liverpool July 4-6 2017
Analysis of an electrical impedance spectroscopy system in short-term digital dermoscopy imaging of melanocytic lesions full article
Rocha, S.W. Menzies, S. Lo, M. Avramidis, R. Khoury, L. Jackett, P.Guitera. British Journal of Dermatology. 19 April 2017. DOI: 10.1111/bjd.15595
Nevisense: Improving the accuracy of diagnosing melanoma, Ollmar S.; Grant S, Melanoma Management (2016) 3:2 (93-96). http://dx.doi.org/10.2217/mmt-2015-0004
Practical application of new technologies for melanoma diagnosis: Part I. Noninvasive approaches March, Hand, Grossman, Journal of the American Academy of Dermatology (2015) 72:6 (929-941). DOI:/10.1016/j.jaad.2015.02.1138
Clinical performance of the Nevisense system in cutaneous melanoma detection: an international, multi-centre, prospective and blinded clinical trial on efficacy and safety full article
Malvehy J, Hauschild A, Curiel-Lewandrowski C, Mohr P, Hofmann-Wellenhof R, Motley R, Berking C, Grossman D, Paoli J, Loquai C, Olah J, Reinhold U, Wenger H, Dirschka T, Davis S, Henderson C, Rabinovitz H, Welzel J, Schadendorf D, Birgersson U. British Journal of Dermatology. 2014 May 19.
DOI: 10.1111/bjd.13121.
Electrical Impedance Spectroscopy as a potential adjunct diagnostic tool for cutaneous melanoma full article
Mohr P, Birgersson U, Berking C, Henderson C, Trefzer U, Kemeny L, Sunderkötter C, Dirschka T, Motley R, Frohm-Nilsson M, Reinhold U, Loquai C, Braun R, Nyberg F, Paoli J. Skin Res Technol. 2013 Jan 27. doi: 10.1111/srt.12008.
Electrical impedance of human skin and tissue alterations: Mathematical modeling and Measurements thesis
Birgersson U. Karolinska Institutet (thesis), Stockholm 2012.
Electrical impedance and the diagnostic accuracy for malignant melanoma abstract
Åberg P, Birgersson U, Elsner P, Mohr P, Ollmar S. Experimental Dermatology, 2011 Mar 3; 648-652.
Non-invasive and microinvasive electrical impedance spectra of skin cancer – a comparison between two techniques abstract Åberg P, Geladi P, Nicander I, Hansson J, Holmgren U, Ollmar S. Skin Res Technol. 2005 Nov;11(4):281-6.
Convalidato nel più ampio studio del genere
Le prestazioni cliniche di Nevisense sono state convalidate in uno studio prospettico pivotale che ha coinvolto 1.951 pazienti e 265 melanomi: lo studio più ampio nel suo genere mai condotto nell’ambito della diagnosi del melanoma. Lo studio ha dimostrato una sensibilità del 97% e un valore predittivo negativo del 99%, fornendo solide prove a sostegno dell’uso di Nevisense come strumento complementare alla valutazione clinica e dermoscopica.

